I read an interview with John Mayer, who has been Jimi Hendrix's tech, in which it was said that a fundamental thing is to calibrate the sound output of the strings making it as uniform as possible: Jimi Hendrix was very careful about this, creating the famous gauge 0.10-0.38 on his strats, and Mayer added that, with respect to this, the importance of the pickups was not that relevant. I think it is an interview that many have already read.
Now I ask myself: can the same be true for Gibsons? I have owned a Gibson ES335 for several years and some time ago I worked on the screws of the PAFs,lowering them in correspondence with the high E and B because I was getting a sound peak (not the note itself), a high timbral crest, a bit metallic which I did not like and, above all, it did not accord with the usual 'softness' of the other strings. This is most noticeable not at high gain boost, but above all when playing clean, at moderate volume. My question is precisely this: is there a gauge that, like the one found by Jimi, can improve the sound output of the Gibson, making the timbre of the strings and their volume more homogeneous? Of course, I know that many factors are involved: maybe the type of strings, the nut, the adjustment of the amp and so on. In any case, thanks to anyone who has such an experience to share